This small work, which came from the Wurts collection, was intended for private use and is sculpted in the round. It depicts St. Anne, seated with an open book in her hands, reading to the Virgin, who is seated with the Child on her lap. The Child reaches out to his grandmother, holding a bunch of grapes, an emblem of Christian faith. The subject is often depicted in a rather static manner, with the three figures seen frontally in a single vertical axis; here, however, the figures are more liberally arranged, allowing a greater range of gestures and emotions to be expressed. Hermanin (1948) attributed it to the 16th century Bavarian school, but Santangelo (1954) believed it was made in Brabant (between Belgium and the Netherlands) around 1510 and he compared it to an analogous work in the Museum of Antwerp (cfr. J. De Bosschère, La sculpture anversoise aux XVe et XVIe siècles, Bruxelles 1909, fig. 18), even though the present work, unlike that in Antwerp, betrays a German influence, from the Rhine region, evident in the handling of the drapery and the overall workmanship. An identical example (47.5 cm.), held in the Deutschen Museum in Berlin (inv. 458), is attributed to the Netherlandish school and dated to the final decade of the 15th century, by the same artist that carved the Palazzo Venezia work. Technical-scientific tests carried out in 2009 by IVALSA-CNR in Florence identified the wood used as tilia (Tilia sp.).